Nikoloz Sainishvili graduated from the Tbilisi State Medical Institute, after which he completed his residency in traumatology, neurosurgery, and radiology. In 2005 he received the degree of Doctor of Medicine.
Over the years, he has held various positions in various medical institutions in Tbilisi. He worked as a neurosurgeon in many clinics and also headed the radiology departments in several hospitals.
Today Nikoloz Sainishvili is the head of the High-Tech Research Center of the Caucasus Medical Center. He is also an active member of the Board of Experts for Oncology/ Hematology of the Evex Hospitals.